Curadel Surgical Innovations (CSI) Moves Flagship Contrast Agent for Image-guided Surgery, ZW800-1, Towards Commercialization

first_imgLocal NewsBusiness By Digital AIM Web Support – February 4, 2021 WhatsApp Previous articleAnna Rix Joins Big Run Studios as Executive ProducerNext articleWine Access Announces Acquisition of Prestigious Napa Valley Wine Merchant 750 Wines Digital AIM Web Support Facebook WhatsApp Pinterest Curadel Surgical Innovations (CSI) Moves Flagship Contrast Agent for Image-guided Surgery, ZW800-1, Towards Commercializationcenter_img NATICK, Mass.–(BUSINESS WIRE)–Feb 4, 2021– Curadel Surgical Innovations Inc., a privately held company specializing in the development of near-infrared fluorescent contrast agents for image-guided surgery, today announced a worldwide distribution deal with a tier one medical technology company to distribute ZW800-1 in the U.S. and EU, upon approval by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) respectively. This news follows the Company’s announcement during the second half of 2020 of a highly prestigious $4 million National Cancer Institute Small Business Innovation Research (SBIR) Phase 2B Bridge Award, granted for the potential widespread use of ZW800-1 in gynecological and other oncologic surgeries. ZW800-1 is an investigational contrast agent for intraoperative anatomical enhancement of the ureters expected to assist surgeons avoid inadvertent damage of these tube-like structures connecting the kidneys to the urinary bladder. ZW800-1 is a first-in-class near-infrared fluorescent (NIR) contrast agents called zwitterionic. The investigational contrast agent, when used in conjunction with an appropriate imaging system, provides contrast by converting NIR light from a lower wavelength to a higher one, visually enhancing the anatomical structure with high sensitivity and specificity. With high brightness and renal-only clearance, a low dose of ZW800-1 has been shown in Phase 2 clinical trials to provide several hours of visualization of the ureters. Currently, intraoperative identification of the ureters during abdominal and pelvic surgeries is extremely difficult. The company is developing additional contrast agents using the FLARE® technology platform to enhance the anatomy of malignant and non-malignant tumors, blood vessels, nerves, lymph nodes, intervertebral discs, and cartilage. “Near-infrared fluorescent light empowers surgeons to see anatomy that would otherwise be invisible, in real-time,” said John V. Frangioni, M.D., Ph.D., Chief Executive Office of Curadel Surgical Innovations. “ZW800-1 is only the beginning of what FLARE® can do for the surgical community.” FLARE® Technology was invented by Dr. Frangioni while he was a professor of medicine and radiology at the Harvard Medical School. The technology is owned by Beth Israel Deaconess Medical Center, a teaching hospital of Harvard Medical School, and is licensed to CSI. About Curadel Surgical Innovations, Inc. Founded in 2014, Curadel Surgical Innovations, Inc. (CSI) is a privately held company headquartered in Natick, Mass. specializing in the development, manufacture, marketing, and commercialization of contrast agents for image-guided surgery. To learn more about Curadel Surgical Innovations, Inc., and its pipeline, please visit View source version on CONTACT: Eliza Schleifstein 917-763-8106 [email protected] KEYWORD: MASSACHUSETTS UNITED STATES NORTH AMERICA INDUSTRY KEYWORD: HEALTH SURGERY MEDICAL SUPPLIES MEDICAL DEVICES SOURCE: Curadel Surgical Innovations Inc. Copyright Business Wire 2021. PUB: 02/04/2021 10:00 AM/DISC: 02/04/2021 10:01 AM Pinterest Twitter Facebook TAGS  Twitterlast_img read more

Water works in pipeline for Buncrana & Twin Towns

first_img Google+ Water works in pipeline for Buncrana & Twin Towns Pinterest Pinterest Twitter WhatsApp Irish Water will shortly submit planning applications to Donegal County Council for upgrades to two separate wastewater treatment schemes in the county.The planning proposals for both Buncrana Sewerage Scheme and Ballybofey-Stranorlar Sewerage Scheme will include upgrades to the sewer network and pumping stations.Irish Water says that these upgrades will address capacity deficiencies and also reduce the risk of sewer flooding and storm overflows.The completed project will also allow for social and economic growth in the surrounding areas, and ensure the treatment of wastewater is fully compliant with current legislation.The planning application for Buncrana which will be submitted shortly, will include provision of storm water storage at the Westbrook Pumping Station and an upgrade to parts of the sewer network to increase its capacity and reduce overflows.Works will take place in the following locations: Cahir O‘Doherty Avenue, Aileach Road, Railway Road, Cockhill Road and Westbrook Pumping Station.Proposed upgrades for the Ballybofey-Stranorlar Sewerage Scheme will include replacement of the existing pumping station at Navenny and flood alleviation measures to protect the site from flooding.The proposed upgrade works will resolve ongoing overflows and flooding from the St Joseph’s Pumping Station. There is also a proposal to upgrade parts of the sewer network to increase its capacity and eliminate overflows.As part of this project works will take place in the following locations: Mill Brae Road, Chapel Lane, Chapel Close, Stranorlar Main Street, Navenny Street, Chestnut Road, St Joseph’s Pumping Station and Navenny Pumping Station. News, Sport and Obituaries on Monday May 24th Arranmore progress and potential flagged as population grows By News Highland – August 26, 2020 Homepage BannerNews Facebookcenter_img WhatsApp Loganair’s new Derry – Liverpool air service takes off from CODA Important message for people attending LUH’s INR clinic RELATED ARTICLESMORE FROM AUTHOR Twitter Previous articleDonegal school principals ‘working round the clock’Next articleBusiness Matters Ep 8 – Paddy Harte News Highland Nine til Noon Show – Listen back to Monday’s Programme DL Debate – 24/05/21 Facebook Google+last_img read more

Jan Cervelli resigns as Saint Mary’s president

first_imgJanice Cervelli resigned from her position as Saint Mary’s College president effective Friday, Oct. 5.Chair of the Board of Trustees Mary Burke announced Cervelli’s resignation in a letter to the Saint Mary’s community Friday. “Earlier this week, Janice Cervelli informed the Board of Trustees of her intent to resign,” Burke said in the letter. “We appreciate all that Jan has contributed to Saint Mary’s during her tenure as President and we wish her the best.”Cervelli took over the role of president in the fall of 2016 after College President Emerita Carol Ann Mooney left. She was officially inaugurated as the 12th Saint Mary’s president Nov. 12, 2016. In an article published May 19, 2017, Cervelli told The Observer she was “doing the most important work of [her] life” as her first year in office ended.Provost Nancy Nekvasil will serve as interim president of the College during the search for a new president.“We are blessed that Dr. Nekvasil will serve as Interim President for as long as needed,” Burke said. “Her rich and esteemed history with Saint Mary’s College as an educator, experienced campus leader, administrator and student advocate speaks volumes. Her accomplishments qualify her for this interim position and empower her to support and uphold our mission and values.” Chair of the department of business Jill Vihtelic will serve as interim provost of the College, and vice president of student affairs Karen Johnson will postpone her retirement to assist with the transition.Burke said the College is appreciative of the support from the campus community during the turnover period. “We are immensely thankful for you, our committed educators and leaders,” Burke said. “Our focus remains positive and centers on our collective spirit to develop strong thinkers through our rigorous academics and supportive community.”Tags: College President, Interim President, Jan Cervelli, Jill Vihtelic, Karen Johnson, Nancy Nekvasil, provost, saint mary’slast_img read more

Shumlin urges participation in Governor’s Career Readiness Certificate Program

first_imgGovernor Peter Shumlin today highlighted the Governor’s Career Readiness Certificate (CRC), which ensures that Vermont workers meet industry-created national training standards to fill cutting edge jobs. He also urged prospective and even current workers and employers to participate in the certificate program to reduce workforce turnover and strengthen the skills and quality of employees.‘In this global economy, Vermont employers require a skilled workforce to compete,’ the Governor said at an appearance at the Cabot Creamery distribution center in Montpelier. ‘Vermont workers who possess those fundamental skills and a solid work ethic are more likely to obtain employment, and once hired, they are more likely to remain employed and advance to higher positions.’The program was established through a partnership between the Community College of Vermont (CCV), the Vermont Department of Labor and the Vermont Agency of Commerce and Community Development. In its first two years, the CRC program served nearly 600 Vermonters.”We are very pleased to have the Governor’s endorsement and namesake on this important tool for qualifying Vermont workers and assisting employers in hiring the right person for the right job,’ said Joyce Judy, President of the Community College of Vermont. ‘Based on a nationally recognized assessment system, CCV has added specific skills based on input from Vermont employers. The Governor’s Career Readiness Certificate is uniquely designed to help Vermonters acquire and demonstrate the skills necessary to thrive in a 21st century economy.”The content of the program includes employer-based recommendations collected through a series of industry forums. The 2011 program now includes three variations, to be delivered in four CCV ‘hub’ locations ‘ Winooski, Rutland, Barre, and Bennington ‘ and other locations as needed:* a 36 hour course (Fast Track CRC)* a 60 hour course (Extended CRC)* Customized sections (Customized CRC) of flexible duration, provided for a specific employer, agency and/or populationStudents who successfully complete all six modules will receive a nationally recognized National WorkKeys Certificate, as well as a CCV Career Readiness Certificate. Unemployed and under-employed individuals are encouraged to participate, and sessions can be customized for employers based on the need for skill upgrades within the current or prospective workforce.‘I am delighted Governor Shumlin is endorsing this program,’ said Patricia Moulton Powden, Deputy Secretary of ACCD. ‘This was developed to respond to the needs of employers who identified these skills as critical for new hires. The work we have all done to get this program launched is enhanced by the Governor’s endorsement.’Employers who have already taken advantage of or will soon be involved in the Career Readiness Certificate program include Cabot Creamery, Green Mountain Coffee Roasters, Vermont Country Store, Central Vermont Medical Center and Rutland Regional Medical Center.last_img read more

Fort St. John RCMP investigating after cab driver assaulted early Sunday

first_imgFort St. John RCMP is looking for a 40 year old Aboriginal male in connection with an assault on a cab driver early Sunday morning. The driver picked up the suspect from the Chevron gas station and was assaulted at the passenger’s destination at the Howard Johnson Hotel at 3:20 a.m.The individual proceeded to throw the driver out of the vehicle and drive away with it. The cab was later discovered abandoned at approximately 6 a.m. around 109 Street in good condition.The taxi driver sustained minor injuries but was taken to hospital and later released.- Advertisement -The suspect is said to have weighed about 220 pounds.Members of the identification section will be examining the vehicle for finger prints as the investigation proceeds.Anyone who may have seen the suspect at the Chevron, the altercation at the hotel, or the suspect driving a grey Pontiac taxi at that time is asked to contact police at 250-787-8100.Advertisementlast_img read more

In Pictures: 300 women bare all at the beach for breast cancer

first_imgIf you were anywhere near the Big White Bay beach at Shroove on Friday night, you could have seen a lot more than expected.That’s because over 300 brave women were taking part in a topless dip!The daring fundraiser created a great buzz in Inishowen this month as women united for a liberating challenge for three important causes. Proceeds from the half strip and dip will go towards Breast Cancer Centre in Letterkenny, Cancer Care West and the Breast Cancer Ireland Schools Outreach Programme. No rain warning could stop the volunteers running into the sea together. The entire event was one big pink party, with many women getting into the spirit by dressing up, getting their friends together and celebrating womanhood.Half-Strip and Dip at Big White Bay Beach. Photo: Nicola Kelly PhotographyKatrina Doherty and Mary McLaughlin, organisers of the Half-Strip and Dip at Big White Bay Beach.Photo: Nicola Kelly PhotographyHalf-Strip and Dip at Big White Bay Beach.Photo: Nicola Kelly PhotographyIt was the ‘breast’ fun, with women aged from 18 to 70 travelling from all over Donegal and as far as Boston, Scotland and Dublin to take the plunge.Katrina Doherty, who organised the event along with Mary McLaughlin, said the night was far beyond anyone’s expectations.“We had 10 busloads taking women out to the beach. The atmosphere was electric and not one person was nervous, they just flung their stuff off. “Maybe the rain helped that. People ran into the water, some people went in twice and some wouldn’t come out again! Some people took their bottom halves off when they were in the water and were swinging them in the air!” Katrina said.Half-Strip and Dip at Big White Bay Beach.Photo: Nicola Kelly PhotographyHalf-Strip and Dip at Big White Bay Beach.Photo: Nicola Kelly PhotographyThe location of the dip was kept closely under wraps to protect the privacy of the volunteers. Buses were parked carefully to cordon off the beach and only females were allowed near the site. The four female members of the Greencastle Coast Guard also came out to keep an eye on everyone.Half-Strip and Dip at Big White Bay Beach. Photo: Nicola Kelly PhotographyHalf-Strip and Dip at Big White Bay Beach.Photo: Nicola Kelly PhotographyHalf-Strip and Dip at Big White Bay Beach.Photo: Nicola Kelly PhotographyThe party didn’t end after the dip was done! Everyone gathered at the Castle Inn in Greencastle for a buffet and a raffle with prizes kindly donated by local businesses. Of course, there was a breast-shaped cake for the occasion. Then the women moved on to Rosato’s in Moville!“We had playlist of great uplifting songs planned for before the dip, the beach and after. We played them all into the wee small hours,” Katrina said.The after-party featured another surprise half-strip – from Katrina’s husband Sean! Sean was sponsored by friends and family to join the stripping sensation that gripped Inishowen last week – he raised a fantastic €1,200 and impressed the crowds at Rosato’s with his half-strip, complete with a pink bra.Amidst all the fun, the event brought hundreds of women together in solidarity with those who have fought breast cancer and it shared an important message to women to ‘check your tatas’.Half-Strip and Dip at Big White Bay Beach.Photo: Nicola Kelly Photography“We’d like to thank all the businesses who got behind us and everyone who supported it and did the dip on the night. The community really got behind us and people are still giving us money, saying that we should be proud of what we have achieved,” Katrina said.The total amount raised is expected to be counted next month, so stay tuned for the grand announcement. If you’d like to support the fundraiser you can also donate online here: Half-Strip and Dip at Big White Bay Beach.Photo: Nicola Kelly PhotographySpecial thanks to Nicola Kelly for capturing the event in pictures, visit her page here: Pictures: 300 women bare all at the beach for breast cancer was last modified: September 4th, 2019 by Rachel McLaughlinShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)Tags:breast cancer awarenessCancer Care Westcharityfundraiserhalf strip and dipInishowenmovillelast_img read more

Jan. 12 Environmental Professionals event will feature Ohio State’s Lonnie Thompson

Share Facebook Twitter Google + LinkedIn Pinterest January’s Environmental Professionals Network breakfast program has a big title for a big topic — in fact, for four very closely related topics.It’s called “Global Warming. You and Me. Energy Audits. Money in Your Pocket. Cleaner Air. More Comfortable Home. Help Is Available. Don’t Procrastinate.”It’s from 7:15 to 9:30 a.m. Jan. 12 in The Ohio State University’s Nationwide and Ohio Farm Bureau 4-H Center, 2201 Fred Taylor Drive in Columbus.And it features talks by four Ohio experts — led by renowned climatologist Lonnie Thompson, Distinguished University Professor in Ohio State’s School of Earth Sciences and senior research scientist with the Byrd Polar and Climate Research Center — on a theme of climate and energy.There also will be a drawing for attendees to win one of five free home energy audits from Columbia Gas of Ohio, but the winners have to live within the company’s service area.Admission to the event, which includes breakfast, is open to both network members and the public. The cost is $10 by cash, check or Ohio State eRequest; $15 by credit card; and free for Ohio State students.Registration and other details are at scheduled talks and speakers are:“Climate Change: The Evidence and Our Options” by Thompson.“Energy Audit and Efficiency Measures Assistance for Homes” by Megan Melby, New Buildings program manager, Demand Side Management, Columbia Gas of Ohio.“Bowling Green Residents Take Energy Efficiency to Heart” by Neocles Leontis, Bowling Green community leader and Bowling Green State University chemistry professor.“OSU’s New Green Home Technology Center Programs” by Eric Romich, energy education field specialist with Ohio State University Extension.The network is a service of Ohio State’s School of Environment and Natural Resources, part of the College of Food, Agricultural, and Environmental Sciences. Romich’s organization, OSU Extension, is the college’s outreach arm.Columbia Gas of Ohio is the event’s sponsor. The school and two other Ohio State units — the Office of Energy and Environment and the Office of Student Life’s Energy Management and Sustainability program — are sponsoring the free student registration. read more

Can IoT prevent gun violence across America’s cities?

first_imgTags:#Data analytics#featured#gun safety#IoT#sensor technology#shotspotter#Smart Cities#top#violence How IoT Will Play an Important Role in Traffic … Related Posts Local municipalities are increasingly turning to smart city technology to reduce public crime through efforts such as connected lighting, targeted surveillance and data assets.One of the more innovative smart solutions is ShotSpotter, a gunshot detection, acoustic surveillance technology that uses sensors to detect, locate and alert law enforcement agencies of illegal gunfire incidents in real time. I spoke to CEO, Ralph A. Clark to learn more.How does it work?ShotSpotter uses acoustic sensors that are strategically placed in an array of 15-20 sensors per square mile in order to reliably detect and accurately triangulate gunshot activity. Each sensor captures the precise time, location, and audio snippet associated with boom and bang sounds (impulsive noise) that may represent a gunshot. This data is first filtered by sophisticated machine algorithms that are then further qualified by experts at the 24×7 Incident Review Center at ShotSpotter to ensure the events are in fact gunfire. As Clark explained:“We have machine classification techniques that we use that can automatically filter out local noises that aren’t gunshots.  And then we process the data through our incident review center. Typically gunfire can be heard as far away as a mile, (unlike fireworks and car backfire) It’s a very distinct noise that has certain sharpness and features that we can extract. Then there’s also the idea of how our sensors participate in the solution. With gunfire you frequently find that the sensor participation is directional. So, it typically happens in a northeast fashion versus a firework which tends to be much more omnidirectional and where the sensor participation will be 360 degrees.”Additionally, Shotspotter can append the alert with any other critical intelligence such as whether a fully automatic weapon was fired. This process takes less than 45 seconds between the actual shooting and the digital alert (with a precise location dot on a map) popping onto the screen of a computer in the 9-1-1 Call Center.Clark noted that Shotspotter had two different use cases:“One is kind of a policing, public safety solution. Which you think of in terms of square miles of coverage. to deal with ongoing, urban violence. The other use case is security use case where you are covering much smaller area and more concerned with the unthinkable happening like an active shooter situation (such on a school campus). It’s more of an alarm type of solution for the rare, if ever, event of an active shooter, And I would say our technology worked very well in both those situations, I mean we’re in the business of detecting, locating and alerting on gun violence in real time and there’s no other company in the world that has our amount of experience dealing in this area in the urban environment.”What is the impact on crime statistics and gun violence?I was curious to learn about how the detection of gun activity could reduce the incidence of gun violence. As Clark discussed:“When you understand how pervasive the problem of gun violence is in many of our cities, there’s certainly a deterrent aspect when you can  can expect a very quick and precise response anytime someone fires a gun. This means that communities suffering from gun violence now begun to see a much more precise, more coordinated respectful response by police to the event. It changes the relationship because now you have communities that aren’t afraid to provide that little bit of insight or intelligence of who they think might be involved in these situations and help police identify and intercept them before they hurt and kill somebody.The other thing about gun violence that is not very well understood by most people is that actually very few people that are driving most of the gunfire. This is not a problem of an entire community where everybody has a gun and everybody shooting. It’s more likely the case that 60 to 70 percent of the Gun violence being perpetrated by a handful of individuals. Like 10 or 20 people, and to deter and prevent and intercept even a small number of those even smaller number of folks that are involved means we see a reduction in shooting.”In New York alone, since deploying ShotSpotter in March 2015, ShotSpotter provided 1,672 alerts on where guns went off, 74% of which, weren’t reported by 911. Cops said ShotSpotter helped recover 32 firearms, including 13 on cases with no 911 call, and has led to 21 arrests. Eight of those arrests had no 911 call.See also: Can a blockchain- IoT hybrid finally give us smart guns?Currently, federal homicide prosecutors are using ShotSpotter analysis and evidence to determine if a gunshot has, or has not occurred, the location of the gunshot, and the precise location of the shooting. SST has been admissible in court cases in 17 states as well as in federal court.  Financially,  Shotspotter is funded through city and police budgets and “often there’s  funding that comes from different federal agencies like the ATF, Department of Homeland Security, or even HIVE they have funds for security that they use to make safer neighborhoods.” Currently, it’s deployed in over 90 cities around the world including San Francisco, Kansas City, and Boston.Interestingly, the company has also been doing some work on conservation in Africa to deter rhino poaching and blast fishing — where explosives are uses in place of nets or fishing line, in effect killing the coral reef as well as the sea life. Shotspotter is a great example of how sensor technology and data analytics can respond to a complex social problem. How Connected Communities Can Bolster Your Busi…center_img Surveillance at the Heart of Smart Cities Cate Lawrence For Self-Driving Systems, Infrastructure and In…last_img read more

Royalty Free Music Playlist: Hypnotic Electro-Pop

first_imgTake a midnight drive to this collection of the best moody electro-pop royalty free music tracks in our music library.These darkly addictive royalty free music tracks are perfect for instilling a thoughtful, pensive feeling throughout your projects. Featuring hypnotic beats and smoldering textures, these electro-pop tracks offer an introspective escape from the rush and pressures of daily life. Royalty free electro-pop can give your project a cool, modern vibe while creating a dreamy atmosphere that’s sure to make you think.If your video project is lacking in vibe, these chilled-out royalty free music tracks curated from the PremiumBeat music library will do the trick. The PremiumBeat Standard License covers most usage, including ALL web video (Facebook, Vimeo, YouTube, etc). Find the perfect royalty free music track below to bring your audience just the right amount of dark atmosphere.last_img read more

Odisha seeks ₹5,200 cr. for cyclone relief

first_imgThe Odisha government has sought early release of ₹5,200 crore from the National Disaster Response Fund for carrying out rehabilitation in areas ravaged by Cyclone Fani.A State government team, led by Chief Secretary Aditya Prasad Padhi, on Thursday held a meeting with a National Disaster Management Authority delegation which had toured the cyclone-affected districts. “We are now in the phase of rehabilitation. The ₹1,000 crore released after Prime Minister’s announcement has been exhausted and we request for early release of ₹5,200 crore from the NDRF,” said Mr. Padhi.The State government has requested the NDMA to direct the telecom companies to have a definite standard operating procedure and preparedness for dealing with disaster situations as communication and data transfer is of crucial importance in relief work.“The disbursement of compensation also suffers due to lack of data connectivity,” said the Chief Secretary.last_img read more